Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5685301 | 0.83 | HSD17B2 (0.54) | ALDH1A1MAPTGAAMAOBMEN1 | |
| SCHEMBL8417819 | 0.83 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2MAPTGAAKDM4E | |
| SCHEMBL8419894 | 0.81 | POLB (0.45) | ALDH1A1SMN1; SMN2KDM4EHTTL3MBTL1 | |
| SCHEMBL6580057 | 0.74 | HSD17B2 (0.67) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL13715441 | 0.72 | KMT2A (0.49) | ALDH1A1SMN1; SMN2MAPTGAAKDM4E | |
| SCHEMBL13715515 | 0.72 | KMT2A (0.49) | ALDH1A1SMN1; SMN2MAPTGAAKDM4E | |
| SCHEMBL3665975 | 0.72 | KMT2A (0.49) | ALDH1A1SMN1; SMN2MAPTGAAKDM4E | |
| SCHEMBL5691331 | 0.71 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MAPTGAAKDM4E | |
| SCHEMBL5670458 | 0.71 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MAPTGAAKDM4E | |
| SCHEMBL12883164 | 0.71 | ACHE (0.59) | ALDH1A1MAPTGAAKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1121718-A | Heterocyclic derivatives | ZENECA LTD (GB) | 1996-05-01 | — | — | CN | disclosed |