Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 9/20 | 0.50 |
| ▸ | FADS1 | O60427 | 3/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27491800 | 0.82 | NAMPT (0.43) | GRM2 | |
| SCHEMBL7520181 | 0.79 | GRM2 (0.48) | GRM2FADS1 | |
| SCHEMBL27490368 | 0.74 | GRM2 (0.35) | GRM2FADS1 | |
| SCHEMBL7237979 | 0.72 | GRM2 (0.65) | GRM2 | |
| SCHEMBL8316448 | 0.72 | GRM2 (0.65) | GRM2 | |
| SCHEMBL2798691 | 0.72 | GRM2 (0.65) | GRM2 | |
| SCHEMBL8948817 | 0.72 | GRM2 (0.65) | GRM2 | |
| SCHEMBL8948639 | 0.72 | GRM2 (0.65) | GRM2 | |
| SCHEMBL7460584 | 0.72 | GRM2 (0.52) | GRM2FADS1 | |
| SCHEMBL2798690 | 0.72 | GRM2 (0.52) | GRM2FADS1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1204889-C | Adhesion receptor antagonists | MERCK PATENT GMBH (DE) | 2005-06-08 | — | — | CN | disclosed |
| CN-1125575-A | Adhesion receptor antagonists | MERCK PATENT GMBH (DE) | 1996-07-03 | — | — | CN | disclosed |