Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 6/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | FADS1 | O60427 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892005 | 0.80 | GRM2 (0.51) | GRM2ARHDAC1HDAC8HDAC6 | |
| SCHEMBL27460280 | 0.79 | GRM2 (0.50) | GRM2FADS1 | |
| SCHEMBL7460584 | 0.76 | GRM2 (0.52) | GRM2HDAC1HDAC8HDAC6FADS1 | |
| SCHEMBL2798690 | 0.76 | GRM2 (0.52) | GRM2HDAC1HDAC8HDAC6FADS1 | |
| SCHEMBL7584426 | 0.76 | EPHX2 (0.47) | GRM2HDAC1ALDH1A1 | |
| SCHEMBL7529594 | 0.74 | BACE1 (0.45) | GRM2 | |
| SCHEMBL8948639 | 0.73 | GRM2 (0.65) | GRM2 | |
| SCHEMBL8948817 | 0.73 | GRM2 (0.65) | GRM2 | |
| SCHEMBL7237979 | 0.73 | GRM2 (0.65) | GRM2 | |
| SCHEMBL9846424 | 0.71 | GRM2 (0.50) | GRM2FADS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697408-B1 | 1 substituted-phenyl-oxazolidene-2-one derivatives and their use as adhesion-receptor antagonists | MERCK PATENT GMBH (DE) | 2002-01-23 | — | — | EP | disclosed |
| EP-0697408-A1 | 1 substituted-phenyl-oxazolidene-2-one derivatives and their use as adhesion-receptor antagonists | MERCK PATENT GmbH (DE) | 1996-02-21 | — | — | EP | disclosed |