Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 0.45 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.48 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 4/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.47 |
| ▸ | RRM1 | P23921 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | PPARD | Q03181 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL27452821 | 0.98 | TSHR (0.50) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| Spermine SCHEMBL1740431 | 0.94 | PAOX (0.56) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| Spermine SCHEMBL27579248 | 0.94 | PAOX (0.56) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| Propionic Acid SCHEMBL28394363 | 0.92 | TSHR (0.52) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| Succinic Acid SCHEMBL27325627 | 0.90 | GPR84 (0.54) | TSHRALDH1A1PAOXPPARGPPARD | |
| Acetic Acid SCHEMBL28361106 | 0.90 | PAOX (0.55) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| Acetic Acid SCHEMBL4073583 | 0.90 | PAOX (0.55) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| Acetic Acid SCHEMBL11789828 | 0.90 | PAOX (0.55) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| Acetic Acid SCHEMBL28238933 | 0.90 | PAOX (0.55) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| Acetic Acid SCHEMBL27657767 | 0.90 | PAOX (0.55) | TSHRALDH1A1S1PR2S1PR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1128578-C | Polymer-type amphoteric disinfectant and its preparing process | CHINA PETROCHEMICAL CORP (CN) | 2003-11-26 | — | — | CN | disclosed |
| CN-1262039-A | Polymer-type amphoteric disinfectant and its preparing process | CHINA PETRO CHEMICAL CO (CN) | 2000-08-09 | — | — | CN | disclosed |