Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 7/20 | 0.48 |
| ▸ | CTSS | P25774 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4862125 | 0.89 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19HTTCTSK | |
| SCHEMBL18397664 | 0.86 | CYP1A2 (0.57) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL20594751 | 0.86 | CTSS (0.57) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL4657580 | 0.85 | CTSK (0.57) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL12069015 | 0.83 | CYP1A2 (0.64) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL12071191 | 0.83 | CYP1A2 (0.64) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL12070120 | 0.83 | CYP1A2 (0.64) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL2617389 | 0.83 | CYP1A2 (0.68) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL7641486 | 0.83 | CYP1A2 (0.68) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL27581318 | 0.83 | CYP1A2 (0.68) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1143859-C | Camptothecin derivative and its preparation | ������ҩ��ʽ���� | 2004-03-31 | — | — | CN | disclosed |
| CN-1075501-C | Camptothecin derivatives, preparation method, intermediate and application | TANABE SEIYAKU CO (JP) | 2001-11-28 | — | — | CN | disclosed |
| CN-1308078-A | Camptothecin derivative and its preparation | TANADE SEIYAKU CO LTD (JP) | 2001-08-15 | — | — | CN | disclosed |
| CN-1145365-A | Camptothecin derivatives | TANABE SEIYAKU CO (JP) | 1997-03-19 | — | — | CN | disclosed |