Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | RORC | P51449 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2528182 | 0.89 | CYP1A2 (0.64) | HSD17B10LMNACYP1A2KDM4EALDH1A1 | |
| SCHEMBL3266897 | 0.89 | CYP1A2 (0.64) | HSD17B10LMNACYP1A2KDM4EALDH1A1 | |
| Water SCHEMBL6057599 | 0.87 | CYP1A2 (0.62) | HSD17B10LMNACYP1A2KDM4EALDH1A1 | |
| SCHEMBL7126585 | 0.85 | HSD17B10 (0.55) | HSD17B10LMNACYP1A2KDM4EALDH1A1 | |
| SCHEMBL8280283 | 0.84 | HSD17B10 (0.53) | HSD17B10LMNACYP1A2KDM4EALDH1A1 | |
| SCHEMBL28040574 | 0.84 | KMT2A (0.55) | HSD17B10LMNACYP1A2KDM4EALDH1A1 | |
| SCHEMBL23205017 | 0.80 | TDP1 (0.55) | HSD17B10LMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL14439930 | 0.80 | POLB (0.50) | HSD17B10LMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL16293544 | 0.80 | KMT2A (0.49) | HSD17B10LMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL1663175 | 0.80 | HSD17B10 (0.60) | HSD17B10LMNACYP1A2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1142492-A | Substituted N-(indole-2-carbonyl)-glycinamides and derivatives as antidiabetic agents | PFIZER (US) | 1997-02-12 | — | — | CN | disclosed |