Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7126585 | 0.89 | HSD17B10 (0.55) | KMT2AHSD17B10LMNAALDH1A1KDM4E | |
| SCHEMBL30100426 | 0.87 | KMT2A (0.59) | KMT2AHSD17B10LMNAALDH1A1MEN1 | |
| SCHEMBL3266897 | 0.85 | CYP1A2 (0.64) | KMT2AHSD17B10LMNAALDH1A1KDM4E | |
| SCHEMBL2528182 | 0.85 | CYP1A2 (0.64) | KMT2AHSD17B10LMNAALDH1A1KDM4E | |
| SCHEMBL28747080 | 0.84 | KMT2A (0.53) | KMT2AHSD17B10LMNAALDH1A1KDM4E | |
| Water SCHEMBL6057599 | 0.84 | CYP1A2 (0.62) | KMT2AHSD17B10LMNAALDH1A1KDM4E | |
| SCHEMBL8280283 | 0.84 | HSD17B10 (0.53) | KMT2AHSD17B10LMNAALDH1A1KDM4E | |
| SCHEMBL27462575 | 0.84 | HSD17B10 (0.53) | KMT2AHSD17B10LMNAALDH1A1KDM4E | |
| SCHEMBL4002644 | 0.82 | GAA (0.54) | KMT2AALDH1A1MEN1SMN1; SMN2MAPT | |
| SCHEMBL3723235 | 0.81 | ALDH1A1 (0.50) | KMT2ALMNAALDH1A1MEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105228982-A | 3-acetylamino-1- (phenyl-heteroaryl-aminocarbonyl or phenyl-heteroaryl-carbonylamino) benzene derivatives for the treatment of hyperproliferative disorders | Bayer Pharma AG | 2016-01-06 | — | — | CN | disclosed |