Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.59 |
| ▸ | CTSK | P43235 | 5/20 | 0.59 |
| ▸ | BCL2 | P10415 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 2/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.51 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8027435 | 1.00 | CTSS (0.59) | CTSSCTSKBCL2CTSBCTSL | |
| SCHEMBL16908256 | 0.97 | CTSS (0.62) | CTSSCTSKCTSBCTSLPPARA | |
| SCHEMBL18813663 | 0.97 | CTSS (0.62) | CTSSCTSKCTSBCTSLPPARA | |
| SCHEMBL7409389 | 0.94 | CTSS (0.65) | CTSSCTSKBCL2CTSBCTSL | |
| SCHEMBL7409385 | 0.94 | CTSS (0.65) | CTSSCTSKBCL2CTSBCTSL | |
| SCHEMBL3826349 | 0.90 | CTSS (0.66) | CTSSCTSKBCL2CTSBCTSL | |
| SCHEMBL85543 | 0.90 | CTSS (0.64) | CTSSCTSKCTSBCTSLPPARA | |
| SCHEMBL3355326 | 0.90 | CTSS (0.64) | CTSSCTSKCTSBCTSLPPARA | |
| SCHEMBL22404737 | 0.90 | CTSS (0.64) | CTSSCTSKCTSBCTSLPPARA | |
| SCHEMBL7235877 | 0.88 | CTSS (0.63) | CTSSCTSKCTSBCTSLPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1138321-A | 1, 3-dialkyl urea derivative with hydrocarbon group | SANTAN PHARMACEUTICAL CO LTD (JP) | 1996-12-18 | — | — | CN | disclosed |