SCHEMBL27464804

SCHEMBL27464804

[CH2]CCCc1c(F)c(F)cc(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA13 Q8N1Q1 1/20 0.33
NOS1 P29475 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6130282 0.79 FFAR4 (0.31)
SCHEMBL19228627 0.76 HTT (0.43) NOS1
SCHEMBL6130301 0.76 TAAR1 (0.37)
SCHEMBL12474303 0.76 CES2 (0.31) NOS1
SCHEMBL1547864 0.74 CA1 (0.33) CA12CA1CA2CA7CA13
SCHEMBL21663934 0.73 ALOX5 (0.43)
SCHEMBL27959455 0.73
SCHEMBL6963717 0.72 TAAR1 (0.52) CA12CA1CA2CA7CA13
SCHEMBL10585053 0.72 TAAR1 (0.36) CA12CA1CA2CA7CA13
SCHEMBL6130256 0.71 TAAR1 (0.42) CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1153774-C Process for refining metallic fluoroaryl compound ��ʽ�����ձ���ý 2004-06-16 CN disclosed
CN-1356330-A Process for refining metallic fluoroaryl compound NIPPON CATALYTIC CHEM IND (JP) 2002-07-03 CN disclosed