Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of Allylbenzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Allylbenzene SCHEMBL18040305 | 0.90 | CNR2 (0.49) | CNR2CYP3A4SMN1; SMN2ALDH1A1TP53 | |
| Allylbenzene SCHEMBL18040306 | 0.90 | CNR2 (0.49) | CNR2CYP3A4SMN1; SMN2ALDH1A1TP53 | |
| Allylbenzene SCHEMBL27290284 | 0.89 | CNR2 (0.51) | CNR2CYP3A4SMN1; SMN2ALDH1A1TP53 | |
| Allylbenzene SCHEMBL11301260 | 0.88 | CNR2 (0.50) | CNR2CYP3A4SMN1; SMN2ALDH1A1TP53 | |
| Allylbenzene SCHEMBL44762 | 0.88 | CNR2 (0.50) | CNR2CYP3A4SMN1; SMN2ALDH1A1TP53 | |
| Allylbenzene SCHEMBL1681576 | 0.86 | CNR2 (0.49) | CNR2CYP3A4SMN1; SMN2ALDH1A1TP53 | |
| Allylbenzene SCHEMBL5983821 | 0.85 | CNR2 (0.46) | CNR2CYP3A4SMN1; SMN2ALDH1A1TP53 | |
| Allylbenzene SCHEMBL7173355 | 0.84 | CNR2 (0.43) | CNR2ALDH1A1L3MBTL1 | |
| Allylbenzene SCHEMBL18550555 | 0.84 | CNR2 (0.43) | CNR2CYP3A4SMN1; SMN2ALDH1A1TP53 | |
| Allylbenzene SCHEMBL876405 | 0.82 | MAOB (0.48) | CNR2CYP3A4SMN1; SMN2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1119362-C | Seed polymerized latex polymer having gradient polymeric morphology and process for preparing the same | JOHNSON & SON INC S C (US) | 2003-08-27 | — | — | CN | disclosed |
| CN-1202181-A | Seed polymerized latex polymer having gradient polymeric morphology and process for preparing the same | JOHNSON & SON INC S C (US) | 1998-12-16 | — | — | CN | disclosed |