SCHEMBL2746535

SCHEMBL2746535

O=C(O)C12CC3CC(C1)CC(C14CC5CC(C#Cc6ccccc6)(CC(C(=O)O)(C5)C1)C4)(C3)C2

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RBP4 P02753 1/20 0.35
GRM5 P41594 4/20 0.34
HSD11B1 P28845 2/20 0.33
KMT2A Q03164 1/20 0.33
GAA P10253 1/20 0.33
PKM P14618 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
P2RX7 Q99572 1/20 0.33
HPGD P15428 1/20 0.32
ALDH1A1 P00352 5/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2707883 0.86 GRM5 (0.38) RBP4GRM5HSD11B1KMT2AP2RX7
Hydrochloric Acid SCHEMBL5000731 0.85 GRM5 (0.37) RBP4GRM5HSD11B1KMT2AL3MBTL1
SCHEMBL2188183 0.84 GRM5 (0.35) GRM5
SCHEMBL2188668 0.81 GRM5 (0.37) GRM5HSD11B1
SCHEMBL2186702 0.80 APP (0.32) GRM5
SCHEMBL2190267 0.79 APP (0.37) GRM5
SCHEMBL5000729 0.79 GRM5 (0.36) GRM5HSD11B1KMT2AL3MBTL1P2RX7
SCHEMBL2746831 0.77 PKM (0.38) RBP4KMT2AGAAPKML3MBTL1
SCHEMBL2192814 0.77 GRM5 (0.35) GRM5
SCHEMBL2187622 0.77 GRM5 (0.35) GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8337982-B2 Comprising first repeating unit obtained by reaction of bisaminophenol compound and dicarboxylic acid, at least one of which has diamondoid structure and second repeating unit obtained by reaction of bisaminophenol compound having no diamondoid structure and dicarboxylic acid; heat resistance SUMITOMO BAKELITE CO., LTD. (JP) 2012-12-25 US disclosed
US-8178631-B2 Resin composition, varnish, resin film and semiconductor device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2012-05-15 US disclosed
US-20090214860-A1 Resin Composition, Varnish, Resin Film and Semiconductor Device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2009-08-27 US disclosed
US-20080206548-A1 Benzoxazole Resin Precursor, Polybenzoxazole Resin, Resin Film And Semiconductor Device SUMITOMO BAKELITE CO., LTD (JP) 2008-08-28 US disclosed
EP-1953181-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Ltd. (JP) 2008-08-06 EP disclosed
EP-1832619-A1 BENZOXAZOLE RESIN PRECURSOR, POLYBENZOXAZOLE RESIN, RESIN FILM, AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Limited (JP) 2007-09-12 EP disclosed