Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | PPID | Q08752 | 2/20 | 0.37 |
| ▸ | PPIB | P23284 | 1/20 | 0.37 |
| ▸ | PPIA | P62937 | 1/20 | 0.37 |
| ▸ | PPIG | Q13427 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2432552 | 0.82 | LMNA (0.42) | CYP1A2LMNACYP3A4MAOASMN1; SMN2 | |
| SCHEMBL5155163 | 0.81 | CYP1A2 (0.41) | CYP1A2LMNACYP3A4MAOASMN1; SMN2 | |
| SCHEMBL20708027 | 0.79 | POLB (0.61) | CYP1A2CYP3A4POLBSMN1; SMN2MEN1 | |
| SCHEMBL6166833 | 0.77 | ALDH1A1 (0.46) | CYP1A2LMNACYP3A4MAOASMN1; SMN2 | |
| SCHEMBL11260308 | 0.76 | LMNA (0.53) | CYP1A2LMNACYP3A4MAOASMN1; SMN2 | |
| SCHEMBL21745741 | 0.75 | SMN1; SMN2 (0.62) | CYP1A2LMNACYP3A4SMN1; SMN2MEN1 | |
| SCHEMBL17420464 | 0.72 | KMT2A (0.35) | CYP1A2LMNAPOLBSMN1; SMN2MEN1 | |
| SCHEMBL5700981 | 0.72 | LMNA (0.41) | CYP1A2LMNACYP3A4MAOAPOLB | |
| SCHEMBL754777 | 0.71 | CYP1A2 (0.56) | CYP1A2LMNACYP3A4MAOAPOLB | |
| SCHEMBL246788 | 0.71 | KMT2A (0.50) | LMNACYP3A4POLBSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1131418-A | Novel fused-ring carboxylic acid compound or salt thereof, and medicinal use thereof | GREEN CROSS CORP (JP) | 1996-09-18 | — | — | CN | disclosed |