Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.44 |
| ▸ | PLAU | P00749 | 2/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27876845 | 0.81 | LOXL2 (0.65) | LOXL2MAPK14PLAUSYKCTSA | |
| SCHEMBL27481686 | 0.78 | MAPK14 (0.55) | LOXL2MAPK14SYK | |
| SCHEMBL27482773 | 0.70 | MAPK14 (0.63) | MAPK14 | |
| SCHEMBL5813696 | 0.68 | MAPK14 (0.60) | MAPK14EGFRMAPK13MAPK12MAPK11 | |
| SCHEMBL16675785 | 0.67 | PRKCI (0.64) | LOXL2MAPK14CTSAFGFR1CDK8 | |
| SCHEMBL3894094 | 0.67 | MAPK14 (0.80) | MAPK14EGFRMAPK13MAPK12MAPK11 | |
| SCHEMBL2642497 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL4892257 | 0.65 | LOXL2 (0.96) | LOXL2 | |
| Hydrochloric Acid SCHEMBL1413435 | 0.65 | LOXL2 (0.96) | LOXL2 | |
| Hydrochloric Acid SCHEMBL31572026 | 0.65 | LOXL2 (0.96) | LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1156471-C | 5-pyridyl-1, 3-azole compounds, their preparation and use | ����ҩƷ��ҵ��ʽ���� | 2004-07-07 | — | — | CN | disclosed |
| CN-1353710-A | 5-pyridyl-1,3-azole compounds, process for producing the same and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-06-12 | — | — | CN | disclosed |