Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5210203 | 0.78 | LMNA (0.41) | L3MBTL1ALDH1A1KDM4ELMNANPSR1 | |
| SCHEMBL27482775 | 0.77 | PTGS2 (0.45) | L3MBTL1LMNANPSR1PTGS2PTGS1 | |
| SCHEMBL27481298 | 0.76 | PTGS2 (0.48) | L3MBTL1ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL27462731 | 0.73 | PTGS2 (0.50) | L3MBTL1LMNANPSR1PTGS2PTGS1 | |
| SCHEMBL28066 | 0.72 | PTGS2 (0.48) | L3MBTL1LMNANPSR1PTGS2PTGS1 | |
| Hydrochloric Acid SCHEMBL27483154 | 0.72 | PTGS2 (0.49) | L3MBTL1LMNANPSR1PTGS2PTGS1 | |
| SCHEMBL27548124 | 0.72 | KDM4E (0.41) | L3MBTL1ALDH1A1KDM4ELMNAHPGD | |
| Hydrochloric Acid SCHEMBL27468627 | 0.72 | PTGS2 (0.47) | L3MBTL1LMNANPSR1PTGS2PTGS1 | |
| SCHEMBL5207597 | 0.71 | PTGS2 (0.40) | L3MBTL1ALDH1A1KDM4ELMNANPSR1 | |
| SCHEMBL27482777 | 0.71 | PTGS2 (0.47) | L3MBTL1LMNANPSR1PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152863-C | Substituted pyridines as selective cyclooxygenase-2 inhibitors | ��˸���˹��(���ô�)��˾ | 2004-06-09 | — | — | CN | disclosed |
| CN-1225085-A | Substituted pyridines as selective cyclooxygenase-2 inhibitors | MERCK FROSST CANADA INC (CA) | 1999-08-04 | — | — | CN | disclosed |