Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18590775 | 0.91 | TAAR1 (0.45) | TAAR1FFAR1FFAR4P2RX7NFE2L2 | |
| SCHEMBL6547406 | 0.87 | TAAR1 (0.48) | TAAR1PYCR1KDM4EALDH1A1TP53 | |
| SCHEMBL18772800 | 0.86 | TAAR1 (0.40) | TAAR1PYCR1FFAR1FFAR4KDM4E | |
| SCHEMBL18772818 | 0.84 | TAAR1 (0.41) | TAAR1FFAR1FFAR4HTTP2RX7 | |
| SCHEMBL27465879 | 0.83 | DAO (0.47) | TAAR1KDM4ESMN1; SMN2NFE2L2 | |
| SCHEMBL24158114 | 0.83 | PYCR1 (0.40) | TAAR1PYCR1KDM4EALDH1A1TP53 | |
| SCHEMBL18458764 | 0.82 | TAAR1 (0.36) | TAAR1FFAR1FFAR4RAB9AP2RX7 | |
| SCHEMBL18499510 | 0.82 | TAAR1 (0.44) | TAAR1FFAR1FFAR4ALDH1A1TDP1 | |
| SCHEMBL18499947 | 0.82 | NOS3 (0.38) | TAAR1FFAR1FFAR4P2RX7 | |
| SCHEMBL19335895 | 0.82 | TAAR1 (0.48) | TAAR1MAPTNFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230025385-A1 | FLUORINATED AROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230025385-A1 | FLUORINATED AROMATIC COMPOUNDS | TRPA1, FOXM1, AFF1 | TAAR1 40/4885PYCR1 2271/4885FFAR1 3189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.