Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27466179 | 1.00 | TDP1 (0.38) | TDP1POLBNPSR1MEN1KMT2A | |
| SCHEMBL27508416 | 0.98 | HDAC4 (0.39) | TDP1POLBNPSR1MEN1KMT2A | |
| SCHEMBL27508415 | 0.98 | HDAC4 (0.39) | TDP1POLBNPSR1MEN1KMT2A | |
| SCHEMBL27468541 | 0.96 | HDAC4 (0.41) | TDP1POLBNPSR1MEN1KMT2A | |
| SCHEMBL27468542 | 0.96 | HDAC4 (0.41) | TDP1POLBNPSR1MEN1KMT2A | |
| SCHEMBL13863591 | 0.80 | MEN1 (0.42) | TDP1POLBNPSR1MEN1KMT2A | |
| SCHEMBL3693813 | 0.79 | MEN1 (0.41) | TDP1POLBNPSR1MEN1KMT2A | |
| SCHEMBL27632265 | 0.77 | SMN1; SMN2 (0.45) | EPHX1 | |
| SCHEMBL10676657 | 0.77 | TDP1 (0.42) | TDP1POLBNPSR1MEN1KMT2A | |
| SCHEMBL1373520 | 0.77 | NPY4R (0.36) | EPHX1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1171116-A | N-substituted glycine derivatives as factor Xa inhibitors | CORVAS INT INC (US) | 1998-01-21 | — | — | CN | disclosed |