Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Sulfide SCHEMBL2746723 | 0.98 | CYP11B1 (0.45) | CYP11B1CYP11B2CHRNB2CHRNA4ALDH1A1 | |
| Hydrogen Sulfide SCHEMBL2746720 | 0.98 | CYP11B1 (0.45) | CYP11B1CYP11B2CHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL21191080 | 0.82 | CYP11B1 (0.44) | CYP11B1CYP11B2CHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL2746564 | 0.81 | NPSR1 (0.38) | ALDH1A1LMNA | |
| SCHEMBL17978217 | 0.79 | CYP11B1 (0.50) | CYP11B1CYP11B2CHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL1961116 | 0.78 | TLR7 (0.33) | — | |
| SCHEMBL487518 | 0.76 | CYP11B1 (0.51) | CYP11B1CYP11B2CHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL2716190 | 0.76 | CYP11B1 (0.51) | CYP11B1CYP11B2CHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL2746674 | 0.75 | MAPT (0.40) | CHRNB2CHRNA4ALDH1A1LMNA | |
| SCHEMBL14205055 | 0.75 | CYP11B1 (0.50) | CYP11B1CYP11B2CHRNB2CHRNA4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141131-A1 | BROMODOMAIN INHIBITOR COMPOUND AND USE THEREOF | 中国科学院上海药物研究所 | 2019-07-25 | — | — | WO | disclosed |
| EP-2079697-B1 | MULTI-SUBSTITUTED PYRIDYL SULFOXIMINES AND THEIR USE AS INSECTICIDES | DOW AGROSCIENCES LLC (US) | 2013-06-05 | — | — | EP | disclosed |
| CN-102870796-A | Multi-substituted pyridyl sulfoximines and their use as insecticides | DOW AGROSCIENCES LLC | 2013-01-16 | — | — | CN | disclosed |
| US-8178565-B2 | Multi-substituted pyridyl sulfoximines and their use as insecticides | DOW AGROSCIENCES LLC (US) | 2012-05-15 | — | — | US | disclosed |
| US-8178565-B2 | Multi-substituted pyridyl sulfoximines and their use as insecticides | DOW AGROSCIENCES LLC (US) | 2012-05-15 | — | — | US | disclosed |
| US-8178565-B2 | Multi-substituted pyridyl sulfoximines and their use as insecticides | DOW AGROSCIENCES LLC (US) | 2012-05-15 | — | — | US | disclosed |
| US-20100179197-A1 | MULTI-SUBSTITUTED PYRIDYL SULFOXIMINES AND THEIR USE AS INSECTICIDES | DOW AGROSCIENCES LLC (US) | 2010-07-15 | — | — | US | disclosed |
| US-20100179197-A1 | MULTI-SUBSTITUTED PYRIDYL SULFOXIMINES AND THEIR USE AS INSECTICIDES | DOW AGROSCIENCES LLC (US) | 2010-07-15 | — | — | US | disclosed |
| US-20100179197-A1 | MULTI-SUBSTITUTED PYRIDYL SULFOXIMINES AND THEIR USE AS INSECTICIDES | DOW AGROSCIENCES LLC (US) | 2010-07-15 | — | — | US | disclosed |
| US-7709649-B2 | Multi-substituted pyridyl sulfoximines and their use as insecticides | DOW AGROSCIENCES LLC (US) | 2010-05-04 | — | — | US | disclosed |
| US-7709649-B2 | Multi-substituted pyridyl sulfoximines and their use as insecticides | DOW AGROSCIENCES LLC (US) | 2010-05-04 | — | — | US | disclosed |
| US-7709649-B2 | Multi-substituted pyridyl sulfoximines and their use as insecticides | DOW AGROSCIENCES LLC (US) | 2010-05-04 | — | — | US | disclosed |
| CN-101535263-A | Polysubstituted pyridyl sulfoximines and their use as pesticides | DOW AGROSCIENCES LLC (US) | 2009-09-16 | — | — | CN | disclosed |
| EP-2079697-A1 | MULTI-SUBSTITUTED PYRIDYL SULFOXIMINES AND THEIR USE AS INSECTICIDES | Dow AgroSciences LLC (US) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008057129-A1 | MULTI-SUBSTITUTED PYRIDYL SULFOXIMINES AND THEIR USE AS INSECTICIDES | DOW AGROSCIENCES LLC (US) | 2008-05-15 | — | — | WO | disclosed |
| WO-2008057129-A1 | MULTI-SUBSTITUTED PYRIDYL SULFOXIMINES AND THEIR USE AS INSECTICIDES | DOW AGROSCIENCES LLC (US) | 2008-05-15 | — | — | WO | disclosed |
| US-20080108667-A1 | Multi-substituted pyridyl sulfoximines and their use as insecticides | CORTEVA AGRISCIENCE LLC | 2008-05-08 | — | — | US | disclosed |
| US-20080108667-A1 | Multi-substituted pyridyl sulfoximines and their use as insecticides | CORTEVA AGRISCIENCE LLC | 2008-05-08 | — | — | US | disclosed |
| US-20080108667-A1 | Multi-substituted pyridyl sulfoximines and their use as insecticides | CORTEVA AGRISCIENCE LLC | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179197-A1 | MULTI-SUBSTITUTED PYRIDYL SULFOXIMINES AND THEIR USE AS INSECTICIDES | PIR, PNPO, PRDX4 | CYP11B1 1145/4885CYP11B2 950/4885CHRNB2 1358/4885 |
| US-20080108667-A1 | Multi-substituted pyridyl sulfoximines and their use as insecticides | PIR, PNPO, PRDX4 | CYP11B1 1145/4885CYP11B2 950/4885CHRNB2 1358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.