Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | BCHE | P06276 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL501720 | 0.90 | ATM (0.76) | KDM4EGAAPKMATML3MBTL1 | |
| SCHEMBL14369843 | 0.89 | ATM (0.74) | KDM4EGAAPKMATML3MBTL1 | |
| SCHEMBL5350446 | 0.89 | ATM (0.74) | KDM4EGAAPKMATML3MBTL1 | |
| SCHEMBL27914544 | 0.88 | GAA (0.66) | KDM4EGAAPKMATML3MBTL1 | |
| SCHEMBL19354714 | 0.84 | L3MBTL1 (0.80) | KDM4EGAAPKMATMTDP1 | |
| SCHEMBL501945 | 0.82 | ATM (0.73) | KDM4EGAAATML3MBTL1ALDH1A1 | |
| SCHEMBL8355590 | 0.81 | CYP2D6 (0.76) | KDM4EGAABCHETDP1ALDH1A1 | |
| SCHEMBL27466577 | 0.81 | BCHE (0.59) | BCHETDP1 | |
| SCHEMBL230276 | 0.81 | NPC1 (0.58) | GAAATML3MBTL1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL8622970 | 0.80 | CYP2D6 (0.74) | KDM4EGAABCHETDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1136556-A | Aromatic group substituted W-amino alkyl amide and alkyl amide | CIBA GEIGY CO LTD (CH) | 1996-11-27 | — | — | CN | disclosed |