Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.43 |
| ▸ | MC4R | P32245 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MC5R | P33032 | 1/20 | 0.41 |
| ▸ | MC3R | P41968 | 1/20 | 0.41 |
| ▸ | MC1R | Q01726 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27468118 | 1.00 | CHRNA7 (0.46) | CHRNA7P2RY12MC4RMEN1KMT2A | |
| SCHEMBL27468116 | 1.00 | CHRNA7 (0.46) | CHRNA7P2RY12MC4RMEN1KMT2A | |
| SCHEMBL27467321 | 0.81 | CTSA (0.46) | P2RY12CYP3A4SMN1; SMN2USP30 | |
| SCHEMBL27468379 | 0.81 | CTSA (0.46) | P2RY12CYP3A4SMN1; SMN2USP30 | |
| SCHEMBL27468378 | 0.81 | CTSA (0.46) | P2RY12CYP3A4SMN1; SMN2USP30 | |
| SCHEMBL27467170 | 0.81 | CCR1 (0.50) | PKMCYP3A4SMN1; SMN2 | |
| SCHEMBL27468243 | 0.81 | CCR1 (0.50) | PKMCYP3A4SMN1; SMN2 | |
| SCHEMBL27468241 | 0.81 | CCR1 (0.50) | PKMCYP3A4SMN1; SMN2 | |
| SCHEMBL27467222 | 0.81 | HDAC3 (0.40) | P2RY12MEN1KMT2ACYP3A4SMN1; SMN2 | |
| SCHEMBL27468115 | 0.81 | ACACB (0.47) | MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024108147-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2024-05-23 | — | — | WO | disclosed |