Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27466064 | 0.78 | SLC1A1 (0.45) | SLC1A1MEN1KMT2AFFAR1PPARG | |
| SCHEMBL6994518 | 0.77 | MAOB (0.45) | SLC1A1ALDH1A1ESR1PPARGPPARA | |
| SCHEMBL8873187 | 0.77 | SLC1A1 (0.56) | SLC1A1MEN1KMT2APPARGPPARA | |
| SCHEMBL27426751 | 0.74 | ESR1 (0.57) | MEN1KMT2AESR1NPC1MAPT | |
| SCHEMBL7173657 | 0.73 | PPARG (0.52) | SLC1A1FFAR1ALDH1A1PPARGPPARA | |
| SCHEMBL28919781 | 0.72 | EPHX1 (0.71) | SLC1A1MEN1KMT2APPARGPPARA | |
| SCHEMBL29609727 | 0.72 | EPHX1 (0.71) | SLC1A1MEN1KMT2APPARGPPARA | |
| SCHEMBL3233609 | 0.72 | TAAR1 (0.47) | ALDH1A1ESR1MAOB | |
| SCHEMBL7817795 | 0.72 | TAAR1 (0.52) | ALDH1A1ESR1MAOB | |
| SCHEMBL9895000 | 0.72 | SLC1A1 (0.48) | SLC1A1MEN1KMT2AALDH1A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1166658-C | 4,5 diaryl-3 (2H) -furanone derivatives as cyclooxygenase-2 inhibitors | ��ʽ����̫ƽ�� | 2004-09-15 | — | — | CN | disclosed |
| CN-1348447-A | 4,5 diaryl-3 (2H) -furanone derivatives as cyclooxygenase-2 inhibitors | PACIFIC CORP (KR) | 2002-05-08 | — | — | CN | disclosed |