Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950224 | 0.85 | CES2 (0.46) | MAOBALDH1A1ESR1MAPTKDM4E | |
| SCHEMBL21087639 | 0.82 | LMNA (0.44) | MAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL3941321 | 0.81 | LMNA (0.47) | HAO1NR1H4MAPTL3MBTL1KDM4E | |
| SCHEMBL4772297 | 0.81 | LMNA (0.47) | HAO1NR1H4MAPTL3MBTL1KDM4E | |
| SCHEMBL570730 | 0.81 | MAPT (0.51) | NR4A2MAPTL3MBTL1SLC1A1CNR2 | |
| SCHEMBL3939694 | 0.81 | MAPT (0.61) | HAO1ALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL6999223 | 0.81 | TAS1R3 (0.42) | MAOBNR4A2ALDH1A1PARP10MAPT | |
| SCHEMBL22733363 | 0.80 | NR4A2 (0.46) | MAOBNR4A2PARP10MAPTL3MBTL1 | |
| SCHEMBL8956315 | 0.80 | L3MBTL1 (0.65) | MAOBNR4A2PPARGPPARAPARP10 | |
| SCHEMBL6511713 | 0.80 | GSK3B (0.46) | MAOBNR4A2PPARDPARP10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109799-B1 | 4,5-DIARYL-3(2H)-FURANONE DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-12-17 | — | — | EP | disclosed |
| US-6492416-B1 | TREATING INFLAMMATION AND ASSOCIATED DISORDERS | PACIFIC CORPORATION (KR) | 2002-12-10 | — | — | US | disclosed |