Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28232905 | 0.91 | CYP3A4 (0.58) | MAPTCYP3A4GAATSHRLMNA | |
| SCHEMBL10956809 | 0.80 | NPC1 (0.55) | ATMHTTMAPTCYP3A4GAA | |
| SCHEMBL4631570 | 0.78 | CYP3A4 (0.72) | CYP3A4TSHRLMNAALDH1A1HPGD | |
| SCHEMBL1625495 | 0.77 | GAA (0.40) | MAPTGAAPOLBRAB9ANPC1 | |
| SCHEMBL3103203 | 0.77 | FAAH (0.54) | HTTMAPTPOLBRAB9ANPC1 | |
| SCHEMBL5167970 | 0.77 | CYP3A4 (0.75) | HTTMAPTCYP3A4GAARAB9A | |
| SCHEMBL21583731 | 0.77 | SMN1; SMN2 (0.62) | HTTMAPTRAB9ANPC1TP53 | |
| SCHEMBL4140012 | 0.77 | RAB9A (0.58) | ATMHTTMAPTCYP3A4GAA | |
| SCHEMBL28326627 | 0.76 | FFAR1 (0.52) | MAPTTP53TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL3815987 | 0.75 | TSHR (0.50) | HTTMAPTCYP3A4GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1138764-C | Isoxazole derivatives | ס����ҩ��ʽ���� | 2004-02-18 | — | — | CN | disclosed |
| CN-1252794-A | Isoxazole derivatives | SUMITOMO PHARMA (JP) | 2000-05-10 | — | — | CN | disclosed |