SCHEMBL2746786

SCHEMBL2746786

C#Cc1cccc(-c2cccc(C(=O)O)c2C(=O)O)c1C#C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.40
FOLH1 Q04609 1/20 0.38
HNF4A P41235 1/20 0.38
PTPN22 Q9Y2R2 2/20 0.37
TSHR P16473 1/20 0.37
ALDH1A1 P00352 4/20 0.37
LMNA P02545 2/20 0.37
MYC P01106 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MAPT P10636 1/20 0.37
ALOX15 P16050 2/20 0.36
PBRM1 Q86U86 1/20 0.36
LIG1 P18858 1/20 0.35
AKR1C3 P42330 1/20 0.34
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2746318 0.87 ALDH1A1 (0.43) HSD17B10FOLH1HNF4ATSHRALDH1A1
SCHEMBL2200319 0.83 ALDH1A1 (0.44) HSD17B10HNF4APTPN22TSHRALDH1A1
SCHEMBL38733 0.83 ALDH1A1 (0.44) HSD17B10FOLH1TSHRALDH1A1LMNA
SCHEMBL30626597 0.83 ALDH1A1 (0.44) HSD17B10HNF4APTPN22TSHRALDH1A1
SCHEMBL5668193 0.81 HSD17B10 (0.48) HSD17B10HNF4APTPN22TSHRALDH1A1
SCHEMBL2746986 0.79 CA12 (0.43) HSD17B10FOLH1HNF4ATSHRALDH1A1
SCHEMBL63603 0.78 HSD17B10 (0.58) HSD17B10FOLH1HNF4ATSHRALDH1A1
SCHEMBL542006 0.78 CDC25B (0.44) HNF4APTPN22TSHRALDH1A1MAPT
Naphthalene SCHEMBL28213983 0.77 NR4A1 (0.47) HSD17B10TSHRALDH1A1LMNAMAPT
SCHEMBL5554145 0.76 HSD17B10 (0.56) HSD17B10FOLH1HNF4ATSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8337982-B2 Comprising first repeating unit obtained by reaction of bisaminophenol compound and dicarboxylic acid, at least one of which has diamondoid structure and second repeating unit obtained by reaction of bisaminophenol compound having no diamondoid structure and dicarboxylic acid; heat resistance SUMITOMO BAKELITE CO., LTD. (JP) 2012-12-25 US disclosed
US-8178631-B2 Resin composition, varnish, resin film and semiconductor device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2012-05-15 US disclosed
US-7608928-B2 Laminated body and semiconductor device JSR CORPORATION (JP) 2009-10-27 US disclosed
US-20090214860-A1 Resin Composition, Varnish, Resin Film and Semiconductor Device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2009-08-27 US disclosed
US-20080206548-A1 Benzoxazole Resin Precursor, Polybenzoxazole Resin, Resin Film And Semiconductor Device SUMITOMO BAKELITE CO., LTD (JP) 2008-08-28 US disclosed
EP-1953181-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Ltd. (JP) 2008-08-06 EP disclosed
US-20080044664-A1 Laminated Body and Semiconductor Drive JSR CORPORATION (JP) 2008-02-21 US disclosed
EP-1832619-A1 BENZOXAZOLE RESIN PRECURSOR, POLYBENZOXAZOLE RESIN, RESIN FILM, AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Limited (JP) 2007-09-12 EP disclosed
EP-1760774-A1 LAMINATED BODY AND SEMICONDUCTOR DEVICE JSR Corporation (JP) 2007-03-07 EP disclosed