Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27450256 | 0.94 | ALDH1A1 (0.41) | KDM4EMAPTMAOBADORA2AHSD17B10 | |
| SCHEMBL27468455 | 0.93 | MAPT (0.46) | KDM4EMAPTMAOBADORA2AALDH1A1 | |
| SCHEMBL27449718 | 0.93 | DHODH (0.42) | KDM4EMAPTMAOBADORA2AHSD17B10 | |
| SCHEMBL27468453 | 0.91 | KMT2A (0.45) | KDM4EMAPTHSD17B10ALDH1A1GAA | |
| SCHEMBL27481472 | 0.90 | RAB9A (0.44) | KDM4ERAB9AALDH1A1KMT2AHTT | |
| SCHEMBL27466584 | 0.88 | KDM4E (0.44) | KDM4EMAPTMAOBADORA2AHSD17B10 | |
| SCHEMBL27467030 | 0.88 | KDM4E (0.41) | KDM4EMAPTMAOBADORA2AHSD17B10 | |
| SCHEMBL27467028 | 0.86 | ALDH1A1 (0.48) | KDM4EMAPTMAOBADORA2AHSD17B10 | |
| SCHEMBL27417159 | 0.80 | DHODH (0.43) | KDM4EMAPTMAOBADORA2AHSD17B10 | |
| SCHEMBL27451146 | 0.78 | KDM4E (0.44) | KDM4EMAPTMAOBADORA2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1188401-C | Heterocyclic amide compound and its pharmaceutical use | MITSUBISHI PHARMACEUTICAL CO L (JP) | 2005-02-09 | — | — | CN | disclosed |
| CN-1131210-C | Heterocyclic amide compound and medical use thereof | MITSUBISHI SEIYAKU CO LTD (JP) | 2003-12-17 | — | — | CN | disclosed |
| CN-1304931-A | Heterocyclic amide compound and medical use thereof | EFUKU CO LTD (JP) | 2001-07-25 | — | — | CN | disclosed |
| CN-1188472-A | Heterocyclic amide compound and medical use thereof | GREEN CROSS CORP (JP) | 1998-07-22 | — | — | CN | disclosed |