Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPY4R | P50391 | 5/20 | 0.34 |
| ▸ | NPY1R | P25929 | 3/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 2/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27468052 | 1.00 | MEN1 (0.39) | MEN1KMT2AGAAMAOAMAOB | |
| SCHEMBL13863591 | 0.82 | MEN1 (0.42) | MEN1KMT2AGAAMAOAMAOB | |
| SCHEMBL19227057 | 0.81 | NPY4R (0.37) | MEN1KMT2ANPY4RNPY1RNPY2R | |
| SCHEMBL19090970 | 0.81 | NPY4R (0.35) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL14228397 | 0.81 | NPY4R (0.35) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL27484588 | 0.81 | MEN1 (0.40) | MEN1KMT2AGAAMAOAMAOB | |
| SCHEMBL27484587 | 0.81 | MEN1 (0.40) | MEN1KMT2AGAAMAOAMAOB | |
| SCHEMBL3693813 | 0.81 | MEN1 (0.41) | MEN1KMT2AGAAMAOAMAOB | |
| SCHEMBL19386721 | 0.80 | NPY4R (0.36) | MEN1KMT2ANPY4RNPY1RNPY2R | |
| SCHEMBL19267172 | 0.80 | NPY4R (0.33) | MEN1KMT2AMAOAMAOBNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1171116-A | N-substituted glycine derivatives as factor Xa inhibitors | CORVAS INT INC (US) | 1998-01-21 | — | — | CN | disclosed |