Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 8/20 | 0.33 |
| ▸ | NPY1R | P25929 | 6/20 | 0.33 |
| ▸ | NPY2R | P49146 | 5/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.30 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.30 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19483435 | 0.82 | ALOX15 (0.36) | NPY4RNPY1RNPY2RNPY5RSIRT6 | |
| SCHEMBL19483434 | 0.82 | ALOX15 (0.36) | NPY4RNPY1RNPY2RNPY5RSIRT6 | |
| SCHEMBL19266923 | 0.82 | — | — | |
| SCHEMBL19090970 | 0.81 | NPY4R (0.35) | NPY4RNPY1RNPY2RNPY5RALOX15 | |
| SCHEMBL19227057 | 0.81 | NPY4R (0.37) | NPY4RNPY1RNPY2RNPY5RSIRT6 | |
| SCHEMBL14228397 | 0.81 | NPY4R (0.35) | NPY4RNPY1RNPY2RNPY5RALOX15 | |
| SCHEMBL19386721 | 0.80 | NPY4R (0.36) | NPY4RNPY1RNPY2RNPY5RALOX15 | |
| SCHEMBL27468053 | 0.80 | MEN1 (0.39) | NPY4RNPY1RNPY2RNPY5RMEN1 | |
| SCHEMBL27468052 | 0.80 | MEN1 (0.39) | NPY4RNPY1RNPY2RNPY5RMEN1 | |
| SCHEMBL4572264 | 0.79 | NPY4R (0.36) | NPY4RNPY1RNPY2RNPY5RSIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432444-B1 | ORAL COMPOSITIONS CONTAINING POLYGUANIDINIUM COMPOUNDS AND METHODS OF MANUFACTURE AND USE THEREOF | COLGATE PALMOLIVE CO (US) | 2017-08-23 | — | — | EP | disclosed |