Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL27468136

N.Oc1ccccc1-c1ncncn1

nearest known ligand 0.48

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.48
IDO1 P14902 4/20 0.46
CASP3 P42574 2/20 0.46
SENP8 Q96LD8 2/20 0.46
SENP7 Q9BQF6 2/20 0.46
SENP6 Q9GZR1 2/20 0.46
MAPK1 P28482 1/20 0.44
ALDH1A1 P00352 4/20 0.43
HSD17B10 Q99714 3/20 0.43
HPGD P15428 3/20 0.43
BCL2L1 Q07817 1/20 0.43
ADORA2A P29274 2/20 0.42
TSHR P16473 2/20 0.42
ALOX15 P16050 2/20 0.42
ADORA3 P0DMS8 1/20 0.42
ADORA2B P29275 1/20 0.42
ADORA1 P30542 1/20 0.42
KMT2A Q03164 2/20 0.41
KDM4A O75164 1/20 0.40
CYP19A1 P11511 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL45750 0.98 SMN1; SMN2 (0.50) SMN1; SMN2IDO1CASP3SENP8SENP7
SCHEMBL29376972 0.98 SMN1; SMN2 (0.50) SMN1; SMN2IDO1CASP3SENP8SENP7
Hydrochloric Acid SCHEMBL30026106 0.96 SMN1; SMN2 (0.48) SMN1; SMN2IDO1CASP3SENP8SENP7
Biphenyl SCHEMBL27881593 0.90 HPGD (0.54) SMN1; SMN2IDO1CASP3SENP8SENP7
SCHEMBL6030984 0.84 IDO1 (0.41) SMN1; SMN2IDO1CASP3SENP8SENP7
SCHEMBL16731968 0.81 ALDH1A1 (0.37) SMN1; SMN2IDO1MAPK1ALDH1A1HSD17B10
SCHEMBL6254344 0.81 HPGD (0.44) SMN1; SMN2IDO1CASP3SENP8SENP7
SCHEMBL29502792 0.80 SMN1; SMN2 (0.55) SMN1; SMN2IDO1CASP3SENP8SENP7
SCHEMBL195151 0.80 SMN1; SMN2 (0.55) SMN1; SMN2IDO1CASP3SENP8SENP7
SCHEMBL679952 0.79 CYP19A1 (0.55) SMN1; SMN2IDO1CASP3SENP8SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1156456-C Hydroxyphenyltriazines ϣ�����⻯ѧ�عɹ�˾ 2004-07-07 CN disclosed
CN-1183410-A Hydroxyphenyltriazines CIBA SC HOLDING AG (CH) 1998-06-03 CN disclosed