Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | FADS1 | O60427 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CALML3 | P27482 | 1/20 | 0.41 |
| ▸ | SDHA | P31040 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28109902 | 0.84 | MAOB (0.43) | USP30HTR6HCRTR1HCRTR2MAOB | |
| SCHEMBL27482756 | 0.82 | GRM2 (0.52) | USP30MAOBMAOAGRM2KMO | |
| SCHEMBL27373749 | 0.81 | MAOB (0.62) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL27483134 | 0.81 | USP30 (0.48) | USP30HTR6MAOBMAOAGRM2 | |
| SCHEMBL27573617 | 0.79 | FADS1 (0.60) | MAOBMAOAGRM2FADS1LMNA | |
| SCHEMBL27573619 | 0.79 | FADS1 (0.60) | MAOBMAOAGRM2FADS1LMNA | |
| SCHEMBL28809356 | 0.79 | F10 (0.60) | USP30HTR6MAOBMAOAGRM2 | |
| SCHEMBL28809355 | 0.79 | F10 (0.60) | USP30HTR6MAOBMAOAGRM2 | |
| SCHEMBL4647204 | 0.79 | MAOB (0.67) | USP30HTR6MAOBMAOAGRM2 | |
| SCHEMBL4647201 | 0.79 | MAOB (0.67) | USP30HTR6MAOBMAOAGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1155585-C | 3, 5-substituted oxazolidinone derivative and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2004-06-30 | — | — | CN | disclosed |
| CN-1355165-A | 3, 5-substituted oxazolidinone derivative and preparation method and application thereof | INST OF MEDICAL BIO TECHNOLOGY (CN) | 2002-06-26 | — | — | CN | disclosed |