Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 8/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CALML3 | P27482 | 1/20 | 0.39 |
| ▸ | SDHA | P31040 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27468588 | 0.84 | USP30 (0.46) | MAOBGRM2USP30MAOAHTR6 | |
| SCHEMBL12006609 | 0.83 | MAOB (0.64) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL12006612 | 0.83 | MAOB (0.64) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL28110426 | 0.81 | PIK3C3 (0.38) | MAOBGRM2MAOA | |
| SCHEMBL23699728 | 0.79 | MAOB (0.41) | MAOBGRM2MAOALMNAPTGS1 | |
| SCHEMBL27483134 | 0.78 | USP30 (0.48) | MAOBGRM2USP30MAOAHTR6 | |
| SCHEMBL28116312 | 0.77 | MAOB (0.63) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL4649482 | 0.76 | MAOB (0.49) | MAOBGRM2USP30MAOALMNA | |
| SCHEMBL5432675 | 0.76 | MAOB (0.49) | MAOBGRM2USP30MAOALMNA | |
| SCHEMBL28809356 | 0.76 | F10 (0.60) | MAOBGRM2USP30MAOAHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104364240-B | A medicine for preventing or treating mycobacterial diseases | 四川贝力克生物技术有限责任公司 | 2017-02-22 | — | — | CN | disclosed |