Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4374968 | 0.84 | CYP1A2 (0.54) | KIF11CYP1A2MEN1KMT2ACYP2C19 | |
| SCHEMBL372366 | 0.84 | KIF11 (0.49) | KIF11SCN5ASCN9ACYP1A2MEN1 | |
| SCHEMBL16586535 | 0.80 | CYP1A2 (0.47) | KIF11SCN5ASCN9ACYP1A2MEN1 | |
| SCHEMBL27481372 | 0.79 | PKM (0.54) | KMT2A | |
| SCHEMBL3664383 | 0.78 | CYP1A2 (0.46) | KIF11SCN5ASCN9ACYP1A2MEN1 | |
| SCHEMBL28419010 | 0.78 | CYP1A2 (0.46) | KIF11SCN5ASCN9ACYP1A2MEN1 | |
| SCHEMBL28419024 | 0.78 | CYP1A2 (0.46) | KIF11SCN5ASCN9ACYP1A2MEN1 | |
| SCHEMBL28416200 | 0.78 | CYP1A2 (0.46) | KIF11SCN5ASCN9ACYP1A2MEN1 | |
| SCHEMBL3664564 | 0.78 | CYP1A2 (0.46) | KIF11SCN5ASCN9ACYP1A2MEN1 | |
| SCHEMBL30028066 | 0.76 | ESR1 (0.47) | KIF11ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1169722-A | 5-lipoxygenase inhibitors | PFIZER (US) | 1998-01-07 | — | — | CN | disclosed |