Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PAM | P19021 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6384412 | 0.90 | ALDH1A1 (0.53) | KMT2AALDH1A1POLBMAPTNPC1 | |
| SCHEMBL10671587 | 0.85 | ALDH1A1 (0.63) | KMT2AALDH1A1POLBMAPTNPC1 | |
| SCHEMBL27594593 | 0.85 | NAPRT (0.54) | KMT2AALDH1A1POLBMAPTNPC1 | |
| SCHEMBL27556286 | 0.83 | ALDH1A1 (0.66) | KMT2AALDH1A1POLBMAPTNPC1 | |
| SCHEMBL2312672 | 0.81 | ALDH1A1 (0.63) | KMT2AALDH1A1POLBMAPTNPC1 | |
| SCHEMBL8484354 | 0.81 | NPC1 (0.63) | KMT2AALDH1A1POLBMAPTNPC1 | |
| SCHEMBL31261505 | 0.80 | ALDH1A1 (0.61) | KMT2AALDH1A1POLBMAPTNPC1 | |
| SCHEMBL16936971 | 0.80 | L3MBTL1 (0.52) | KMT2AALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL27516923 | 0.80 | TSHR (0.53) | KMT2AALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL4315070 | 0.80 | ALDH1A1 (0.61) | KMT2AALDH1A1POLBMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1155278-A | Arylthio compounds as antibacteral and antiviral agents | WARNER LAMBERT CO (US) | 1997-07-23 | — | — | CN | disclosed |