Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27484586 | 0.73 | CHRM3 (0.34) | KIF11 | |
| SCHEMBL7389768 | 0.67 | MAPK1 (0.57) | MTNR1AMTNR1BL3MBTL1TDP1 | |
| SCHEMBL6302107 | 0.66 | MTNR1A (0.59) | CASRMTNR1AMTNR1BAOC3L3MBTL1 | |
| SCHEMBL15923316 | 0.66 | MAPK1 (0.56) | MTNR1AMTNR1BL3MBTL1TDP1 | |
| SCHEMBL29696901 | 0.66 | MAPK1 (0.56) | MTNR1AMTNR1BL3MBTL1TDP1 | |
| SCHEMBL8552109 | 0.66 | MAPK1 (0.56) | MTNR1AMTNR1BL3MBTL1TDP1 | |
| SCHEMBL4450023 | 0.64 | KCNA5 (0.51) | CASRMTNR1AMTNR1BAOC3L3MBTL1 | |
| SCHEMBL4450026 | 0.64 | KCNA5 (0.51) | CASRMTNR1AMTNR1BAOC3L3MBTL1 | |
| SCHEMBL6891571 | 0.64 | KIF11 (0.48) | KIF11 | |
| SCHEMBL7784227 | 0.64 | AOC3 (0.66) | CASRMTNR1AMTNR1BAOC3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1167437-A | Method of using triaryl-ethylene derivatives in the treatment and prevention of osteoporosis | HOECHST MARION ROUSSEL INC (US) | 1997-12-10 | — | — | CN | disclosed |