SCHEMBL27469259

SCHEMBL27469259

OC(O)Oc1cncnc1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.33
GRM5 P41594 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27938987 0.74 CYP19A1 (0.32)
SCHEMBL12896055 0.74 CHRNB2 (0.38)
SCHEMBL27941156 0.74
SCHEMBL9242002 0.74 LMNA (0.39) HCAR2GRM5
Hydrochloric Acid SCHEMBL28162383 0.72 CHRNB2 (0.37)
SCHEMBL27925995 0.70
SCHEMBL13074971 0.65
SCHEMBL25418672 0.65 HCAR2 (0.36) HCAR2
Ethyne SCHEMBL27176504 0.65 EGFR (0.41) GRM5
SCHEMBL166230 0.64 MEN1 (0.64)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110240601-A Synthesis method of penoxsulam intermediate 湖北广富林生物制剂有限公司 2019-09-17 CN claimed
CN-106243045-A A kind of preparation method of 2,5 dimethoxy 4 aminopyrimidines 常州大学 2016-12-21 CN claimed
CN-101486684-B Preparation of 2,4-dichloro-5-methoxy pyrimidine CHANGZHOU HUAYI CHEMICAL CO LTD 2010-11-10 CN claimed
CN-110240601-A Synthesis method of penoxsulam intermediate 湖北广富林生物制剂有限公司 2019-09-17 CN disclosed
CN-108658871-A The preparation method of sulfamethoxine intermediate 4,6- dichloro-5-methoxy pyrimidines 张家港威胜生物医药有限公司 2018-10-16 CN disclosed
CN-106243045-A A kind of preparation method of 2,5 dimethoxy 4 aminopyrimidines 常州大学 2016-12-21 CN disclosed
CN-102060782-A Method for preparing chloropyrimidines or analogues thereof ZHIHUA SUN 2011-05-18 CN disclosed
CN-1085556-A The 4-pyrimidyl and the pyridinyl derivatives of the indol-3-yl alkylpiperazine of anti-migraine BRISTOL MYERS SQUIBB CO (US) 1994-04-20 CN disclosed