SCHEMBL27469262

SCHEMBL27469262

O=C(OC(C(F)(F)F)C(F)(F)F)c1ccc(C(=O)OC(C(F)(F)F)C(F)(F)F)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.45
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
CA7 P43166 2/20 0.45
CA9 Q16790 2/20 0.45
CA14 Q9ULX7 2/20 0.45
TSHR P16473 2/20 0.42
TP53 P04637 1/20 0.42
PDCD1 Q15116 1/20 0.41
CD274 Q9NZQ7 1/20 0.41
GABRA1 P14867 2/20 0.40
GABRG2 P18507 2/20 0.40
GABRB3 P28472 2/20 0.40
GABRA5 P31644 2/20 0.40
GABRA3 P34903 2/20 0.40
GABRA2 P47869 2/20 0.40
GABRA4 P48169 2/20 0.40
GABRA6 Q16445 2/20 0.40
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17230527 0.92 CA12 (0.58) CA12CA1CA2CA7CA9
SCHEMBL22181192 0.90 CA1 (0.52) CA12CA1CA2CA7CA9
SCHEMBL4763671 0.90 TSHR (0.57) TSHRTP53PDCD1CD274GABRA1
SCHEMBL16738393 0.87 CA1 (0.56) CA1CA2ABHD6KMT2ACES2
SCHEMBL17111061 0.86 CA12 (0.41) CA12CA1CA2CA7CA9
SCHEMBL17111059 0.86 NPC1 (0.40) CA12CA1CA2CA7CA9
SCHEMBL18312749 0.86 HSD17B10 (0.48) TSHRGABRA1GABRG2GABRB3GABRA5
SCHEMBL17230484 0.84 KMT2A (0.54) CA12CA1CA2CA7CA9
SCHEMBL17093438 0.84 GABRA1 (0.43) TSHRTP53GABRA1GABRG2GABRB3
SCHEMBL25696180 0.83 TP53 (0.42) TSHRTP53PDCD1CD274GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1103954-A Molded article of graded refractive index exhibiting low dispersion HOECHST CELANESE CORP (US) 1995-06-21 CN claimed