Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27625801 | 0.94 | TP53 (0.46) | TSHRALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL27523184 | 0.94 | NPC1 (0.48) | TSHRCA2CA12CA1CA7 | |
| SCHEMBL27926554 | 0.92 | LMNA (0.56) | TSHRLMNACYP1A2CYP2C19MAPK1 | |
| SCHEMBL28180841 | 0.92 | LMNA (0.49) | TSHRLMNAALDH1A1CYP3A4PRKCA | |
| SCHEMBL28876436 | 0.91 | CA1 (0.49) | TSHRCA2CA1NPC1RAB9A | |
| SCHEMBL27493314 | 0.89 | TSHR (0.43) | TSHRMAPK1ESR1ALDH1A1PRKCA | |
| SCHEMBL27513083 | 0.89 | LMNA (0.49) | LMNACYP1A2CYP2C19CYP2D6SMN1; SMN2 | |
| SCHEMBL28318339 | 0.88 | UTS2R (0.49) | TSHRLMNACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL27429967 | 0.87 | PRKCA (0.47) | TSHRCYP1A2CYP2C19MAPK1SMN1; SMN2 | |
| SCHEMBL28318307 | 0.86 | TSHR (0.48) | TSHRMAPK1ESR1ALDH1A1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105536708-B | A kind of advanced composite material (ACM) and preparation method thereof based on metal-organic framework materials and carbon nanotube | 北京林业大学 | 2018-09-11 | — | — | CN | claimed |
| CN-100379792-C | Process for manufacture of functionalized polyphenylene ethers | GEN ELECTRIC (US) | 2008-04-09 | — | — | CN | claimed |
| CN-113136739-B | Method for improving interface bonding strength of aramid fiber mica paper | 陕西科技大学 | 2023-02-24 | — | — | CN | disclosed |
| CN-113136739-A | Method for improving interface bonding strength of aramid fiber mica paper | 陕西科技大学 | 2021-07-20 | — | — | CN | disclosed |
| CN-100462389-C | Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin | MITSUI CHEMICALS INC (JP) | 2009-02-18 | — | — | CN | disclosed |
| CN-100379792-C | Process for manufacture of functionalized polyphenylene ethers | GEN ELECTRIC (US) | 2008-04-09 | — | — | CN | disclosed |
| CN-1630676-A | Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin | MITSUI CHEMICALS INC (JP) | 2005-06-22 | — | — | CN | disclosed |
| CN-1104939-C | High permeability composite reverse osmosis film and reverse osmosis film assembly with it | NITTO DENKO CORP (JP) | 2003-04-09 | — | — | CN | disclosed |
| CN-1103625-C | High-permeability composite reverse osmosis membrane and reverse osmosis membrane assembly using same | NITTO DENKO CORP (JP) | 2003-03-26 | — | — | CN | disclosed |
| CN-1334838-A | Process for the preparation of functionalized polyphenylene ethers | GEN ELECTRIC (US) | 2002-02-06 | — | — | CN | disclosed |
| CN-1170627-A | High permeability composite reverse osmosis film and reverse osmosis film assembly with it | NITTO DENKO CORP (JP) | 1998-01-21 | — | — | CN | disclosed |
| CN-1163793-A | High-permeability composite reverse osmosis membrane and reverse osmosis membrane assembly using same | NITTO DENKO CORP (JP) | 1997-11-05 | — | — | CN | disclosed |