Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27469364 | 0.98 | ALDH1A1 (0.50) | ALDH1A1ESR1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL27487172 | 0.82 | KMT2A (0.43) | ALDH1A1ESR1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL27502344 | 0.80 | KMT2A (0.42) | ALDH1A1ESR1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL11783974 | 0.80 | KMT2A (0.38) | ALDH1A1ESR1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL2810981 | 0.79 | ALDH1A1 (0.47) | ALDH1A1ESR1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL3045678 | 0.77 | KMT2A (0.46) | ALDH1A1ESR1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL27586781 | 0.77 | HSP90AA1 (0.57) | ALDH1A1HPGDHSP90AA1FAAHCA1 | |
| SCHEMBL11778545 | 0.75 | KMT2A (0.48) | ALDH1A1ESR1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL11325801 | 0.75 | KMT2A (0.44) | ALDH1A1ESR1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL18281626 | 0.73 | KMT2A (0.61) | ALDH1A1KMT2ATSHRSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1161128-C | Angiogenic inhibitory compounds | О | 2004-08-11 | — | — | CN | claimed |
| CN-1134486-C | Antiviral dendrimers | BIOMOLECULAR RES INST LTD (AU) | 2004-01-14 | — | — | CN | claimed |
| CN-1225654-A | Angiogenic inhibitory compounds | BIOMOLECULAR RES INST LTD (AU) | 1999-08-11 | — | — | CN | claimed |
| CN-1154123-A | Antiviral dendrimers | BIOMOLECULAR RES INST LTD (AU) | 1997-07-09 | — | — | CN | claimed |
| CN-1161128-C | Angiogenic inhibitory compounds | О | 2004-08-11 | — | — | CN | disclosed |
| CN-1134486-C | Antiviral dendrimers | BIOMOLECULAR RES INST LTD (AU) | 2004-01-14 | — | — | CN | disclosed |
| CN-1154123-A | Antiviral dendrimers | BIOMOLECULAR RES INST LTD (AU) | 1997-07-09 | — | — | CN | disclosed |