SCHEMBL3045678

SCHEMBL3045678

O=C(O)N(c1ccccc1)S(=O)(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.46
NPSR1 Q6W5P4 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.41
TSHR P16473 2/20 0.41
ALDH1A1 P00352 4/20 0.40
LMNA P02545 2/20 0.40
TP53 P04637 1/20 0.40
CDK1 P06493 1/20 0.39
CCNB1 P14635 1/20 0.39
CCNA2 P20248 1/20 0.39
CCND1 P24385 1/20 0.39
CDK2 P24941 1/20 0.39
CDK7 P50613 1/20 0.39
CCNH P51946 1/20 0.39
CCNA1 P78396 1/20 0.39
CDK6 Q00534 1/20 0.39
HSP90AA1 P07900 1/20 0.38
ESR1 P03372 1/20 0.38
HPGD P15428 1/20 0.38
NPC1 O15118 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11325801 0.84 KMT2A (0.44) KMT2ANPSR1SMN1; SMN2TSHRALDH1A1
SCHEMBL18281626 0.83 KMT2A (0.61) KMT2ANPSR1SMN1; SMN2TSHRALDH1A1
SCHEMBL27487172 0.83 KMT2A (0.43) KMT2ANPSR1SMN1; SMN2TSHRALDH1A1
SCHEMBL27502344 0.81 KMT2A (0.42) KMT2ANPSR1SMN1; SMN2TSHRALDH1A1
SCHEMBL4748576 0.80 KMT2A (0.44) KMT2ANPSR1SMN1; SMN2TSHRALDH1A1
SCHEMBL11492117 0.80 CA2 (0.45) KMT2ANPSR1SMN1; SMN2TSHRALDH1A1
SCHEMBL11778545 0.80 KMT2A (0.48) KMT2ANPSR1SMN1; SMN2TSHRALDH1A1
SCHEMBL28290788 0.78 KMT2A (0.40) KMT2ANPSR1SMN1; SMN2TSHRALDH1A1
SCHEMBL27469362 0.77 ALDH1A1 (0.52) KMT2ANPSR1SMN1; SMN2TSHRALDH1A1
SCHEMBL11783974 0.77 KMT2A (0.38) KMT2ANPSR1SMN1; SMN2TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100221502-A1 Anthrapyridone Compound and Salt Thereof, Magenta Ink Composition Containing the Anthrapyridone Compound, and Colored Article NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2010-09-02 US claimed
US-7223301-B2 Anthrapyridone compound, water-based magenta ink composition and inkjet recording method NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2007-05-29 US claimed
US-20060219131-A1 Anthrapyridone compound, aqueous magenta ink composition and inkjet recording method NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2006-10-05 US claimed
EP-1626069-A1 ANTHRAPYRIDONE COMPOUND, AQUEOUS MAGENTA INK COMPOSITION AND INKJET RECORDING METHOD NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2006-02-15 EP claimed
EP-0036838-B1 AZO DYESTUFFS, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1984-09-26 EP claimed
US-4447357-A Fibre-reactive azo dyestuffs containing a halotriazinyl radical and a non-reactive triazinyl radical CIBA-GEIGY CORPORATION (US) 1984-05-08 US claimed
EP-0036838-A2 Azo dyestuffs, their preparation and their use CIBA-GEIGY AG (CH) 1981-09-30 EP claimed
US-4269773-A CEPHALOSPORINS SHIONOGI & CO., LTD. (JP) 1981-05-26 US claimed
US-20100221502-A1 Anthrapyridone Compound and Salt Thereof, Magenta Ink Composition Containing the Anthrapyridone Compound, and Colored Article NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2010-09-02 US disclosed
US-7223301-B2 Anthrapyridone compound, water-based magenta ink composition and inkjet recording method NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2007-05-29 US disclosed
US-20060219131-A1 Anthrapyridone compound, aqueous magenta ink composition and inkjet recording method NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2006-10-05 US disclosed
EP-1626069-A1 ANTHRAPYRIDONE COMPOUND, AQUEOUS MAGENTA INK COMPOSITION AND INKJET RECORDING METHOD NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2006-02-15 EP disclosed
EP-0036838-B1 AZO DYESTUFFS, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1984-09-26 EP disclosed
US-4447357-A Fibre-reactive azo dyestuffs containing a halotriazinyl radical and a non-reactive triazinyl radical CIBA-GEIGY CORPORATION (US) 1984-05-08 US disclosed
EP-0036838-A2 Azo dyestuffs, their preparation and their use CIBA-GEIGY AG (CH) 1981-09-30 EP disclosed
US-4269773-A CEPHALOSPORINS SHIONOGI & CO., LTD. (JP) 1981-05-26 US disclosed
US-4159984-A METAL AND PROTON DONOR SHIONOGI & CO., LTD. (JP) 1979-07-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100221502-A1 Anthrapyridone Compound and Salt Thereof, Magenta Ink Composition Containing the Anthrapyridone Compound, and Colored Article ABL1, ATXN2L, ANXA7 KMT2A 774/4885NPSR1 2390/4885SMN1; SMN2 4721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.