SCHEMBL27469609

SCHEMBL27469609

O=C(C(O)C(O)C(O)C(O)CO)S(=O)(=O)O.[Au]

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.55
PDE4A P27815 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.46
TDP1 Q9NUW8 1/20 0.44
USP2 O75604 1/20 0.41
SLCO1B1 Q9Y6L6 1/20 0.41
KDM4E B2RXH2 2/20 0.34
TP53 P04637 1/20 0.31
MGAM O43451 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27316941 0.98 LMNA (0.57) LMNAPDE4AL3MBTL1TDP1USP2
SCHEMBL979873 0.98 LMNA (0.57) LMNAPDE4AL3MBTL1TDP1USP2
SCHEMBL9108031 0.98 LMNA (0.57) LMNAPDE4AL3MBTL1TDP1USP2
SCHEMBL27480900 0.96 LMNA (0.55) LMNAPDE4AL3MBTL1TDP1USP2
SCHEMBL31544298 0.96 LMNA (0.55) LMNAPDE4AL3MBTL1TDP1USP2
SCHEMBL27521459 0.94 LMNA (0.47) LMNAPDE4AL3MBTL1TDP1USP2
SCHEMBL30469495 0.91 LMNA (0.48) LMNAPDE4AL3MBTL1TDP1USP2
SCHEMBL27604552 0.91 LMNA (0.48) LMNAPDE4AL3MBTL1TDP1USP2
Piperazine SCHEMBL27952189 0.87 LMNA (0.47) LMNAPDE4AL3MBTL1TDP1USP2
SCHEMBL9651828 0.83 PDE4A (0.58) LMNAPDE4AL3MBTL1TDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105142639-A IRAK inhibitors and uses thereof NIMBUS IRIS INC 2015-12-09 CN disclosed
CN-105025870-A Composition comprising a metal oxide and a metal oxide SYMRISE AG 2015-11-04 CN disclosed
CN-102281862-B Benzylidene compounds comprising phosphono groups BASF SE 2015-04-15 CN disclosed
CN-104349768-A Compositions comprising apomorphine and organic acids and uses thereof NEURODERM LTD 2015-02-11 CN disclosed
CN-102458379-B Functional amphiphilic molecule or macromolecule formulations with multiple compartments UNIV VICTOR SEGALEN BORDEAUX 2 2014-05-14 CN disclosed
CN-102448450-B Compositions comprising trans-tert-butyl cyclohexanol as skin irritation-reducing agent SYMRISE GMBH & CO KG 2013-11-20 CN disclosed
CN-101932310-B Method for preparing nanoparticles based on functional amphiphilic molecules or macromolecules, and the use thereof UNIV VICTOR SEGALEN BORDEAUX 2 2013-11-13 CN disclosed
CN-102458379-A Multicompartmentalized formulations based on functional amphiphilic molecules or macromolecules UNIV VICTOR SEGALEN BORDEAUX 2 2012-05-16 CN disclosed
CN-102281862-A Benzylidene compounds comprising phosphono groups 2011-12-14 CN disclosed
CN-102002102-A Body weight modulators, corresponding nucleic acids and proteins, and their use for diagnosis and therapy UNIV ROCKEFELLER 2011-04-06 CN disclosed
CN-100561336-C Silver-halide color photoelement and formation method FUJI PHOTO FILM CO LTD (JP) 2009-11-18 CN disclosed
CN-100456131-C Silver halide emulsionand silver halide color camera photosensitive material FUJI PHOTO FILM CO LTD (JP) 2009-01-28 CN disclosed
CN-101321745-A Nitrogen-containing heterocyclic compound and pharmaceutical application thereof ONO PHARMACEUTICAL CO (JP) 2008-12-10 CN disclosed
CN-101167016-A Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 2008-04-23 CN disclosed
CN-101048700-A Silver halide color photographic light-sensitive material and image forming method FUJIFILM CORP (JP) 2007-10-03 CN disclosed
CN-1950748-A Bleach concentrate composition for silver halide color- photographic materials, one-part type concentrate composition for replenishment color developers, and method of processing FUJI PHOTO FILM CO LTD (JP) 2007-04-18 CN disclosed
CN-1550886-A Silver halide colour photosensitive material and imaging method ��ʿ��Ƭ��ʽ���� 2004-12-01 CN disclosed
CN-1530741-A Silver halide emulsion and silver halide camera photosensitive material 富士胶片株式会社 2004-09-22 CN disclosed
CN-1530742-A Silver halide emulsionand silver halide color camera photosensitive material 富士胶片株式会社 2004-09-22 CN disclosed
CN-1162978-A Body weight regulators, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof UNIV ROCKEFELLER (US) 1997-10-22 CN disclosed