2-Pyrrolidone

2-Pyrrolidone

SCHEMBL27469716

C=C(C)C(=O)OC(C)N(CC)CC.O=C1CCCN1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.39
FKBP5 Q13451 1/20 0.34
CRBN Q96SW2 1/20 0.34
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Pyrrolidone SCHEMBL28096599 0.85 OR51E2 (0.42) OR51E2FKBP5CRBN
2-Pyrrolidone SCHEMBL12468588 0.81 OR51E2 (0.46) OR51E2FKBP5CRBNTSHR
SCHEMBL14873 0.80 TSHR (0.44) TSHR
SCHEMBL28273631 0.80 TSHR (0.44) TSHR
2-Pyrrolidone SCHEMBL28304484 0.80 OR51E2 (0.44) OR51E2FKBP5CRBNTSHR
Ammonia Solution, Strong SCHEMBL28263372 0.79 TSHR (0.42) TSHR
Hydrochloric Acid SCHEMBL9258461 0.79 TSHR (0.42) TSHR
Chloromethane SCHEMBL1128070 0.77 TSHR (0.41) TSHR
Isopropyl Alcohol SCHEMBL20480785 0.77 TSHR (0.41) TSHR
Acetic Acid SCHEMBL27216306 0.77 TSHR (0.41) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1193729-C Cosmetic composition containing specific polysaccharide resin OREAL (FR) 2005-03-23 CN disclosed
CN-1165275-C Cosmetic composition containing block copolymer ŷ���Źɷ����޹�˾ 2004-09-08 CN disclosed
CN-1372454-A Cosmetic composition containing specific polysaccharide resin OREAL (FR) 2002-10-02 CN disclosed
CN-1341010-A Cosmetic composition containing block copolymer OREAL (FR) 2002-03-20 CN disclosed