SCHEMBL27469772

SCHEMBL27469772

N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)cs1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SSTR1 P30872 1/20 0.54
HTR2A P28223 2/20 0.49
ADRB1 P08588 1/20 0.49
HTR1A P08908 1/20 0.49
ADRA2A P08913 1/20 0.49
SLC6A2 P23975 1/20 0.49
HTR1D P28221 1/20 0.49
HTR1B P28222 1/20 0.49
HTR2C P28335 1/20 0.49
HTR1E P28566 1/20 0.49
SLC6A4 P31645 1/20 0.49
HTR7 P34969 1/20 0.49
HTR2B P41595 1/20 0.49
HTR6 P50406 1/20 0.49
SLC6A3 Q01959 1/20 0.49
KDM4E B2RXH2 5/20 0.48
MEN1 O00255 5/20 0.48
KMT2A Q03164 5/20 0.48
MAPT P10636 5/20 0.48
LMNA P02545 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27469773 1.00 SSTR1 (0.54) SSTR1HTR2AADRB1HTR1AADRA2A
Hydrochloric Acid SCHEMBL6715553 0.99 SSTR1 (0.53) SSTR1HTR2AADRB1HTR1AADRA2A
Hydrochloric Acid SCHEMBL27548729 0.99 SSTR1 (0.53) SSTR1HTR2AADRB1HTR1AADRA2A
SCHEMBL3800552 0.83 HTR2A (0.55) SSTR1HTR2AADRB1HTR1AADRA2A
SCHEMBL3799963 0.83 HTR2A (0.55) SSTR1HTR2AADRB1HTR1AADRA2A
SCHEMBL1926329 0.80 KCNT1 (0.46) SSTR1MEN1KMT2ALMNAGPR84
SCHEMBL6718770 0.80 AIMP2 (0.49) SSTR1KDM4EMEN1KMT2AMAPT
SCHEMBL27584284 0.80 KCNT1 (0.46) SSTR1MEN1KMT2ALMNAGPR84
Bromide SCHEMBL6441067 0.79 HTR2A (0.50) SSTR1HTR2AADRB1HTR1AADRA2A
SCHEMBL1928394 0.79 SSTR1 (0.63) SSTR1HTR2AADRB1HTR1AADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1169808-C Beta-carboline compounds �о���Ӧ�ÿ�ѧЭ��ɷ����޹�˾ 2004-10-06 CN disclosed
CN-1308632-A 'Beta'-carboline compound CONSEILS DE RES ES ET D APPLIC (FR) 2001-08-15 CN disclosed