SCHEMBL27469798

SCHEMBL27469798

NC(=O)Oc1ccccc1-c1ccc(N)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCOA1 Q15788 1/20 0.50
NCOA3 Q9Y6Q9 1/20 0.50
FABP3 P05413 3/20 0.45
FABP7 O15540 2/20 0.45
FABP5 Q01469 2/20 0.45
PTGDR2 Q9Y5Y4 1/20 0.40
TDP1 Q9NUW8 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
BCAT2 O15382 1/20 0.39
CYP3A4 P08684 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
DRD1 P21728 2/20 0.36
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
RXRG P48443 1/20 0.36
LMNA P02545 1/20 0.36
FFAR4 Q5NUL3 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31448682 0.87 FABP3 (0.49) NCOA1NCOA3FABP3FABP7FABP5
SCHEMBL274364 0.87 FABP3 (0.53) NCOA1NCOA3FABP3FABP7FABP5
SCHEMBL20573270 0.86 SLC6A4 (0.50) FABP3FABP7FABP5DRD1LMNA
SCHEMBL3790378 0.84 NCOA1 (0.49) NCOA1NCOA3FABP3FABP7FABP5
SCHEMBL17796918 0.84 SLC6A4 (0.49) FABP3FABP7FABP5PTGDR2TDP1
SCHEMBL7647143 0.84 LMNA (0.50) FABP3FABP7FABP5PTGDR2TDP1
SCHEMBL27615625 0.84 MKNK1 (0.49) TDP1L3MBTL1BCAT2CYP3A4HSD17B10
SCHEMBL29728528 0.82 KMT2A (0.46) FABP3FABP7FABP5TDP1L3MBTL1
SCHEMBL17797004 0.81 MAOA (0.44) NCOA1NCOA3FABP3FABP7FABP5
SCHEMBL20573425 0.81 IRAK4 (0.45) FABP3FABP7FABP5PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1165531-C Alpha-methylbenzyl-containing thiourea inhibitors of herpes viruses containing phenylenediamine groups 2004-09-08 CN disclosed
CN-1367785-A Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing substituted phenylenediamine groups AMERICAN HOME PROD (US) 2002-09-04 CN disclosed
CN-1348446-A Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing phenylenediamine groups AMERICAN HOME PROD (US) 2002-05-08 CN disclosed
CN-1335843-A Thiourea inhibitors of herpes viruses AMERICAN HOME PROD (US) 2002-02-13 CN disclosed
CN-1333769-A Thiourea inhibitors of herps viruses AMERICAN HOME PROD (US) 2002-01-30 CN disclosed
CN-1333750-A Acetamide and substituted acetamide-containing thiourea inhibitors of herpes viruses AMERICAN HOME PROD (US) 2002-01-30 CN disclosed
CN-1332725-A Thiourea inhibitors of herpes viruses AMERICAN HOME PROD (US) 2002-01-23 CN disclosed
CN-1329608-A Alpha-methylbenzyl-containing thioure a inhibitors of herpes viruses containing phenylenediamine group AMERICAN HOME PROD (US) 2002-01-02 CN disclosed