Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15129377 | 0.85 | CTSD (0.53) | CTSDNPC1RAB9AL3MBTL1STAT3 | |
| SCHEMBL28897069 | 0.84 | CTSD (0.51) | CTSDNPC1RAB9AL3MBTL1STAT3 | |
| SCHEMBL25211437 | 0.84 | CTSD (0.56) | CTSDNPC1RAB9AL3MBTL1STAT3 | |
| SCHEMBL2486631 | 0.82 | CTSD (0.54) | CTSDNPC1RAB9AL3MBTL1STAT3 | |
| SCHEMBL27914867 | 0.82 | CTSD (0.54) | CTSDNPC1RAB9AL3MBTL1STAT3 | |
| SCHEMBL2541558 | 0.79 | CTSD (0.55) | CTSDNPC1RAB9AL3MBTL1STAT3 | |
| SCHEMBL27478744 | 0.78 | RAB9A (0.54) | CTSDNPC1RAB9AL3MBTL1STAT3 | |
| SCHEMBL24634050 | 0.78 | HTT (0.53) | CTSDNPC1RAB9AL3MBTL1STAT3 | |
| SCHEMBL27508679 | 0.76 | HTT (0.66) | CTSDNPC1RAB9AL3MBTL1STAT3 | |
| SCHEMBL307126 | 0.76 | CTSD (0.51) | CTSDNPC1RAB9AL3MBTL1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1148357-C | Triazole and imidazole derivative | - | 2004-05-05 | — | — | CN | disclosed |
| CN-1281852-A | Triazole and imidazole derivative | HOFFMANN LA ROCHE (CH) | 2001-01-31 | — | — | CN | disclosed |
| CN-87105457-A | BENZOHYDROXAMIC ACID DERIVATIVES | — | 1988-02-17 | — | — | CN | disclosed |