SCHEMBL27469898

SCHEMBL27469898

O=C(CCCc1ccc(Cl)c(Cl)c1)CCCc1ccc(Cl)c(Cl)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IGF1R P08069 1/20 0.58
ALOX15 P16050 1/20 0.58
PYGL P06737 1/20 0.57
TRPV1 Q8NER1 2/20 0.55
PNMT P11086 1/20 0.52
TAAR1 Q96RJ0 1/20 0.52
IDO1 P14902 1/20 0.50
GRIN1 Q05586 1/20 0.49
GRIN2B Q13224 1/20 0.49
PDPK1 O15530 1/20 0.49
HDAC6 Q9UBN7 1/20 0.48
SIGMAR1 Q99720 4/20 0.47
PLAAT3 P53816 1/20 0.47
PLAAT5 Q96KN8 1/20 0.47
PLAAT2 Q9NWW9 1/20 0.47
PLAAT4 Q9UL19 1/20 0.47
FFAR1 O14842 1/20 0.46
TSHR P16473 1/20 0.46
MAOB P27338 1/20 0.45
IAPP P10997 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7330823 0.88 PYGL (0.60) IGF1RALOX15PYGLTRPV1PNMT
SCHEMBL1694247 0.87 TRPV1 (0.57) IGF1RALOX15PYGLTRPV1PNMT
SCHEMBL6078543 0.87 IGF1R (0.56) IGF1RALOX15PYGLTRPV1PNMT
SCHEMBL11039081 0.85 TRPV1 (0.56) IGF1RALOX15PYGLTRPV1PNMT
SCHEMBL7338732 0.85 IGF1R (0.54) IGF1RALOX15PYGLTRPV1PNMT
SCHEMBL14829867 0.85 IGF1R (0.54) IGF1RALOX15PYGLTRPV1PNMT
SCHEMBL8221813 0.81 L3MBTL1 (0.58) IGF1RALOX15PYGLTRPV1PNMT
SCHEMBL11363170 0.81 TRPV1 (0.52) IGF1RALOX15PYGLTRPV1PNMT
SCHEMBL10835218 0.81 IGF1R (0.50) IGF1RALOX15PYGLTRPV1PNMT
SCHEMBL11274932 0.81 PYGL (0.57) IGF1RALOX15PYGLTRPV1PNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1315780-C Process for producing n-(1-(2,4-dichlorophenyl)ethyl)-2- cyano-3,3-dimethylbutanamide SUMITOMO CHEMICAL CO (JP) 2007-05-16 CN disclosed
CN-1243720-C Process for producing n-(1-(2,4-dichlorophenyl)ethyl)-2- cyano-3,3-dimethylbutanamide SUMITOMO CHEMICAL CO (JP) 2006-03-01 CN disclosed
CN-1243719-C Process for producing N- [1- (2, 4-dichlorophenyl) ethyl ] -2-cyano-3, 3-dimethylbutanamide SUMITOMO CHEMICAL CO (JP) 2006-03-01 CN disclosed
CN-1680273-A Process for producing n-(1-(2,4-dichlorophenyl)ethyl)-2- cyano-3,3-dimethylbutanamide SUMITOMO CHEMICAL CO (JP) 2005-10-12 CN disclosed
CN-1526696-A Process for producing N- [ 1- (2, 4-dichlorophenyl) ethyl ] -2-cyano-3, 3-dimethylbutanamide 住友化学工业株式会社 2004-09-08 CN disclosed
CN-1524845-A Process for producing n-(1-(2,4-dichlorophenyl)ethyl)-2- cyano-3,3-dimethylbutanamide 住友化学工业株式会社 2004-09-01 CN disclosed
CN-1153762-C Process for producing N- [1- (2, 4-dichlorophenyl) ethyl ] -2-cyano-3, 3-dimethylbutanamide 住友化学工业株式会社 2004-06-16 CN disclosed
CN-1131146-A Process for producing N- [1- (2, 4-dichlorophenyl) ethyl ] -2-cyano-3, 3-dimethylbutanamide SUMITOMO CHEMICAL CO (JP) 1996-09-18 CN disclosed