Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 2/20 | 0.33 |
| ▸ | CDK8 | P49336 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | LPO | P22079 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27821978 | 0.79 | BRD4 (0.41) | BRD4MC4RHTR2CHTR2AKDM4E | |
| SCHEMBL19029699 | 0.75 | BRD4 (0.53) | BRD4MC4RHTR2CHTR2AKDM4E | |
| SCHEMBL13360249 | 0.72 | MC4R (0.46) | BRD4MC4RHTR2CHTR2AKDM4E | |
| SCHEMBL8672845 | 0.72 | BRD4 (0.40) | BRD4MC4RHTR2CHTR2AKDM4E | |
| SCHEMBL31039260 | 0.70 | BRD4 (0.41) | BRD4MC4RHTR2CHTR2AKDM4E | |
| SCHEMBL13878871 | 0.68 | BRD4 (0.39) | BRD4MC4RHTR2CHTR2AKDM4E | |
| SCHEMBL31485961 | 0.67 | MYC (0.42) | BRD4MC4RHTR2CHTR2ACDK8 | |
| SCHEMBL15011218 | 0.67 | SCN9A (0.41) | BRD4MC4RKDM4ENPC1RAB9A | |
| SCHEMBL16656630 | 0.67 | MC4R (0.40) | BRD4MC4RHTR2CHTR2ACCNC | |
| SCHEMBL28343831 | 0.67 | MC4R (0.53) | BRD4MC4RHTR2CHTR2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1149874-A | Cephalosporin antibiotics | MICROCIDE PHARMACEUTICALS INC (US) | 1997-05-14 | — | — | CN | disclosed |