Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31039260 | 0.87 | BRD4 (0.41) | BRD4KCNH2MC4RP2RX7HTR2C | |
| SCHEMBL31439827 | 0.83 | BRD4 (0.43) | BRD4P2RX7HTR2CHTR2AKMT2A | |
| SCHEMBL5796145 | 0.83 | BRD4 (0.43) | BRD4P2RX7HTR2CHTR2AKMT2A | |
| SCHEMBL14960647 | 0.81 | HSD11B1 (0.54) | BRD4MC4RP2RX7HSD11B1GRM1 | |
| SCHEMBL27470748 | 0.79 | BRD4 (0.40) | BRD4MC4RHTR2CHTR2AKDM4E | |
| SCHEMBL31319322 | 0.78 | MC4R (0.41) | BRD4MC4RHTR2CHTR2AKMT2A | |
| SCHEMBL19029699 | 0.76 | BRD4 (0.53) | BRD4MC4RHTR2CHTR2AKMT2A | |
| SCHEMBL15803554 | 0.76 | MAPK14 (0.43) | BRD4MC4RP2RX7HTR2CHTR2A | |
| SCHEMBL13878871 | 0.75 | BRD4 (0.39) | BRD4MC4RHTR2CHTR2AKDM4E | |
| SCHEMBL13360249 | 0.73 | MC4R (0.46) | BRD4MC4RHTR2CHTR2AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102906089-A | Compounds for the treatment of hepatitis C | BRISTOL MYERS SQUIBB CO | 2013-01-30 | — | — | CN | disclosed |
| CN-102209711-A | Compounds for the treatment of hepatitis c | BRISTOL MYERS SQUIBB CO | 2011-10-05 | — | — | CN | disclosed |