Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28343831 | 0.80 | MC4R (0.53) | MC4RBRD4GABRG2GABRB3GABRA5 | |
| SCHEMBL27007893 | 0.74 | HSD11B1 (0.47) | CRHR1KDM4EPOLBHPGDHCAR1 | |
| SCHEMBL13587950 | 0.74 | BRD4 (0.56) | BRD4L3MBTL1HTR2CHTR2AKDM4E | |
| SCHEMBL2326291 | 0.74 | IDO1 (0.47) | MC4RBRD4KDM4EPKMALDH1A1 | |
| SCHEMBL20761804 | 0.74 | CCR1 (0.41) | MC4RBRD4L3MBTL1GABRG2GABRB3 | |
| SCHEMBL1806063 | 0.74 | BRD4 (0.41) | MC4RBRD4L3MBTL1HTR2CHTR2A | |
| SCHEMBL27821978 | 0.73 | BRD4 (0.41) | MC4RBRD4HTR2CHTR2AKDM4E | |
| SCHEMBL3489826 | 0.72 | NMT1 (0.47) | MC4RBRD4KDM4EALDH1A1MAPT | |
| SCHEMBL27470748 | 0.72 | BRD4 (0.40) | MC4RBRD4L3MBTL1HTR2CHTR2A | |
| SCHEMBL2945910 | 0.72 | S100A4 (0.46) | ALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718087-B2 | Organic iridium compositions and their use in electronic devices | GENERAL ELECTRIC COMPANY (US) | 2010-05-18 | — | — | US | disclosed |
| US-7718277-B2 | Electronic devices comprising organic iridium compositions | GENERAL ELECTRIC COMPANY (US) | 2010-05-18 | — | — | US | disclosed |
| US-7704610-B2 | organic light emitting device comprising deuterated organic iridium complex; optoelectronic devices, photovoltaic devices; enhanced color properties and light output efficiencies | GENERAL ELECTRIC COMPANY (US) | 2010-04-27 | — | — | US | disclosed |
| US-7695640-B2 | Organic iridium compositions and their use in electronic devices | GENERAL ELECTRIC COMPANY (US) | 2010-04-13 | — | — | US | disclosed |
| US-7691292-B2 | organic light emitters; photovoltaic cells; electrophosphorescent | GENERAL ELECTRIC COMPANY (US) | 2010-04-06 | — | — | US | disclosed |
| US-7691494-B2 | Electronic devices comprising organic iridium compositions | GENERAL ELECTRIC COMPANY (US) | 2010-04-06 | — | — | US | disclosed |
| US-7652151-B2 | Ketopyrroles useful as ligands in organic iridium compositions | GENERAL ELECTRIC COMPANY (US) | 2010-01-26 | — | — | US | disclosed |
| US-7608677-B2 | Method for preparing polymeric organic iridium compositions | GENERAL ELECTRIC COMPANY (US) | 2009-10-27 | — | — | US | disclosed |
| US-20080023672-A1 | Organic iridium compositions and their use in electronic devices | GENERAL ELECTRIC COMPANY | 2008-01-31 | — | — | US | disclosed |
| US-20080026249-A1 | Electronic devices comprising organic iridium compositions | GENERAL ELECTRIC COMPANY | 2008-01-31 | — | — | US | disclosed |
| US-20080023671-A1 | Organic iridium compositions and their use in electronic devices | GENERAL ELECTRIC COMPANY | 2008-01-31 | — | — | US | disclosed |
| US-20080026250-A1 | Electronic devices comprising organic iridium compositions | GENERAL ELECTRIC COMPANY | 2008-01-31 | — | — | US | disclosed |
| US-20080027028-A1 | Ketopyrroles useful as ligands in organic iridium compositions | GENERAL ELECTRIC COMPANY | 2008-01-31 | — | — | US | disclosed |
| US-20080026477-A1 | Method for preparing polymeric organic iridium compositions | GENERAL ELECTRIC COMPANY (US) | 2008-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027028-A1 | Ketopyrroles useful as ligands in organic iridium compositions | OR10J3, OPRD1, OCIAD1 | MC4R 274/4885BRD4 114/4885L3MBTL1 2136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.