Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27381632 | 0.98 | CA2 (0.45) | CA2MAPK1CA1GPR84FFAR1 | |
| SCHEMBL27400263 | 0.98 | CA2 (0.45) | CA2MAPK1CA1GPR84FFAR1 | |
| SCHEMBL27345960 | 0.93 | CA2 (0.54) | CA2MAPK1CA1SLC1A2SLC1A1 | |
| SCHEMBL18100109 | 0.88 | CA2 (0.48) | CA2GPR84FFAR1LMNAGRIK1 | |
| SCHEMBL11762017 | 0.81 | CA2 (0.47) | CA2MAPK1CA1GPR84FFAR1 | |
| SCHEMBL27984986 | 0.80 | CA2 (0.50) | CA2MAPK1CA1GPR84LMNA | |
| SCHEMBL13121888 | 0.79 | CA2 (0.54) | CA2MAPK1CA1LMNAGRIK1 | |
| SCHEMBL30437067 | 0.79 | CA2 (0.45) | CA2MAPK1CA1GPR84LMNA | |
| SCHEMBL10995430 | 0.78 | CA2 (0.48) | CA2MAPK1CA1GPR84FFAR1 | |
| SCHEMBL5933413 | 0.78 | CA2 (0.48) | CA2MAPK1CA1GPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1178927-C | Histamine H3 receptor ligands | ��ղķ˹����Ƕ� | 2004-12-08 | — | — | CN | disclosed |
| CN-1296478-A | Histamine H3 receptor ligands | BLACK JAMES FOUNDATION (GB) | 2001-05-23 | — | — | CN | disclosed |