SCHEMBL27474201

SCHEMBL27474201

CNC1Nc2ccc(-c3coc(C#N)c3)cc2C(NC)(NC)O1

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PGR P06401 20/20 0.59
AR P10275 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27458362 0.80 PGR (0.59) PGR
SCHEMBL27475124 0.79 PGR (0.60) PGRAR
SCHEMBL27460739 0.78 PGR (0.61) PGRAR
SCHEMBL27475125 0.78 PGR (0.49) PGR
SCHEMBL27475511 0.77 PGR (0.60) PGRAR
SCHEMBL27460738 0.76 PGR (0.51) PGRAR
SCHEMBL27458364 0.76 PGR (0.61) PGRAR
SCHEMBL27474721 0.74 PGR (0.56) PGR
SCHEMBL6777073 0.74 PGR (1.00) PGRAR
SCHEMBL27512067 0.74 PGR (0.56) PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1145610-C Quinazolinone and benzoxazine derivatives as progesterone receptor modulators 美国家庭用品有限公司 2004-04-14 CN claimed
CN-1145610-C Quinazolinone and benzoxazine derivatives as progesterone receptor modulators 美国家庭用品有限公司 2004-04-14 CN disclosed
CN-1349508-A Quinazolinone and benzoxazine derivatives as progesterone receptor modulators AMERICAN HOME PROD (US) 2002-05-15 CN disclosed