Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 20/20 | 0.60 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.50 |
| ▸ | AR | P10275 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27475511 | 0.83 | PGR (0.60) | PGRNR3C1AR | |
| SCHEMBL27458364 | 0.82 | PGR (0.61) | PGRNR3C1NR3C2AR | |
| SCHEMBL27458362 | 0.79 | PGR (0.59) | PGR | |
| SCHEMBL27474201 | 0.79 | PGR (0.59) | PGRAR | |
| SCHEMBL27460739 | 0.77 | PGR (0.61) | PGRNR3C1NR3C2AR | |
| SCHEMBL27475125 | 0.77 | PGR (0.49) | PGR | |
| SCHEMBL27460738 | 0.75 | PGR (0.51) | PGRNR3C1NR3C2AR | |
| SCHEMBL6888773 | 0.75 | PGR (1.00) | PGRNR3C1NR3C2AR | |
| SCHEMBL27474721 | 0.74 | PGR (0.56) | PGR | |
| SCHEMBL27512067 | 0.74 | PGR (0.56) | PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1145610-C | Quinazolinone and benzoxazine derivatives as progesterone receptor modulators | 美国家庭用品有限公司 | 2004-04-14 | — | — | CN | claimed |
| CN-1145610-C | Quinazolinone and benzoxazine derivatives as progesterone receptor modulators | 美国家庭用品有限公司 | 2004-04-14 | — | — | CN | disclosed |
| CN-1349508-A | Quinazolinone and benzoxazine derivatives as progesterone receptor modulators | AMERICAN HOME PROD (US) | 2002-05-15 | — | — | CN | disclosed |