Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | KRAS | P01116 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL27474750 | 0.89 | CNR1 (0.48) | MCL1NOTUMCNR2CNR1 | |
| Ethoxycarbonyl Group SCHEMBL27528310 | 0.76 | NOTUM (0.38) | NOTUMKRAS | |
| SCHEMBL27474220 | 0.70 | MCL1 (0.43) | MCL1S1PR1FABP4FABP5ADRA1D | |
| SCHEMBL27587633 | 0.69 | HTR2C (0.56) | MCL1S1PR1FABP4FABP5TERT | |
| Ethoxycarbonyl Group SCHEMBL27490855 | 0.69 | CREBBP (0.44) | MCL1FABP4CNR1 | |
| SCHEMBL7947029 | 0.68 | FABP4 (0.49) | FABP4FABP5CNR2 | |
| SCHEMBL418623 | 0.68 | STAT3 (0.50) | FABP4FABP5TERT | |
| SCHEMBL13668164 | 0.67 | CDK4 (0.41) | MCL1NOTUMADRA1DKRASADRA1A | |
| SCHEMBL13311382 | 0.67 | NOTUM (0.50) | NOTUMKRASCNR2CNR1 | |
| SCHEMBL1269116 | 0.66 | CDK4 (0.71) | FABP4FABP5TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1161334-A | Novel substd. guanidine derivs., process for prodn. thereof, and pharmaceutical uses thereof | SUMITOMO PHARMA (JP) | 1997-10-08 | — | — | CN | disclosed |